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Updated: May 15, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Acute Osteomyelitis with Deep Vein Thrombosis in Children: A Case Series of MRSA-Associated Infections
Manjunatha Mahamani1, Sandesh F Akki1, Arvind D Patil1
1Department of Orthopaedics, SDM College of Medical Sciences and Hospital, Shri Dharmasthala Manjunatheshwara University, Dharwad, Karnataka, India.
Introduction:
Acute osteomyelitis (AOM) is a common pediatric infection; however, its association with deep vein thrombosis (DVT) is rare and often underdiagnosed due to overlapping symptoms.
Case Report:
We report three pediatric cases (mean age 9.3 years) of femoral AOM complicated by DVT, all due to methicillin-resistant Staphylococcus aureus (MRSA). Fever, limb pain, and swelling were the presenting triad in all patients. Magnetic resonance imaging confirmed osteomyelitis with abscess, and Doppler ultrasound or computed tomography venogram detected DVT. Management included surgical drainage with cortical decompression and anticoagulation therapy. All patients achieved complete recovery within 10-12 months.
Conclusion:
Severe femoral osteomyelitis, particularly when MRSA-positive, should prompt clinicians to consider concurrent DVT. Early combined imaging and intervention can prevent serious complications and ensure optimal functional outcomes.
Insights
Acute osteomyelitis, a common pediatric bone infection, can rarely be associated with deep vein thrombosis (DVT). This case series highlights three pediatric patients with femoral osteomyelitis and DVT, emphasizing early diagnosis and treatment for full recovery.
Area of Science:
- Pediatric Infectious Diseases
- Vascular Thrombotic Disorders
- Musculoskeletal Infections
Background:
- Acute osteomyelitis (AOM) is a frequent pediatric infection.
- Its association with deep vein thrombosis (DVT) is uncommon and frequently overlooked due to similar symptoms.
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