Related Experiment Video
Updated: May 15, 2026
07:56
Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
Association between multiple urinary trace metal elements and lumbar bone mineral density in adults
Renhao Zhang1,2, Tianyu Fu1,2, Fengyue Guo1
1The first Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Nagoya Journal of Medical Science
|May 14, 2026
Summary
Urinary trace metals like cesium, antimony, and tin show positive links to bone mineral density (BMD). However, barium exposure has an inverted U-shaped association with BMD in US adults.
Area of Science:
- Environmental health
- Toxicology
- Bone metabolism
Background:
- Urinary trace metals are biomarkers for toxic metal exposure and linked to osteoporosis.
- Limited epidemiological data exists on trace metal exposure and adult bone mineral density (BMD).
Purpose of the Study:
- To investigate the association between urinary trace metal elements and BMD in US adults.
- To identify specific trace metals impacting bone health.
Main Methods:
- Cross-sectional study of 3,441 adults (2018 NHANES).
- Analysis of four urinary trace metals: barium, cesium, antimony, and tin.
- Weighted multivariable logistic regression, subgroup, smoothing curve, and threshold effect analyses were performed.
Main Results:
- Urinary cesium, antimony, and tin were positively associated with lumbar BMD.
- Urinary barium showed an inverted U-shaped association with BMD.
- Significant associations were observed in US adults aged 20-59.
Conclusions:
- Specific urinary trace metals (cesium, antimony, tin) are linked to higher lumbar BMD.
- Barium exposure exhibits a complex, non-linear relationship with BMD.
- Findings aid in developing bone mineral density management strategies.
More Related Videos
Related Concept Videos
01:29Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
01:31Essential Minerals for Bone Health
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
01:27Urinary Tract Calculi IV: Nutrition Therapy and Prevention
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
01:30Urinary Tract Calculi III: Medical Management
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
01:28Urinary Tract Calculi I: Introduction
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...