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Overstaffing and Understaffing Are Associated With Adverse Events In a Level III Neonatal Intensive Care Unit.

Lilli Ristevirta1, Outi Tuominen2, Eliisa Löyttyniemi3

  • 1Department of Nursing Science, University of Turku.

Journal of Patient Safety
|May 14, 2026
PubMed
Summary

Optimal nurse-to-patient ratios (NPR) in neonatal intensive care units (NICUs) are crucial for preventing adverse events (AEs). Both understaffing and overstaffing increase the risk of AEs, highlighting the need for careful staffing to ensure patient safety.

Keywords:
adverse eventneonatal intensive care unit (NICU)nurse-to-patient ratioretrospective register study

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Area of Science:

  • Neonatal Intensive Care Unit (NICU) Nursing
  • Patient Safety Research
  • Healthcare Management

Background:

  • Adverse events (AEs) in neonatal intensive care units (NICUs) pose significant risks to vulnerable infants.
  • The nurse-to-patient ratio (NPR) is a critical factor influencing patient safety and care quality.
  • Understanding the relationship between staffing levels and AEs is essential for optimizing NICU operations.

Purpose of the Study:

  • To evaluate the association between the nurse-to-patient ratio (NPR) and the occurrence of adverse events (AEs) in a level III NICU.
  • To identify specific staffing conditions (understaffing, overstaffing) associated with increased AEs.
  • To explore unit-specific factors contributing to AEs, such as shift overlaps and shift times.

Main Methods:

  • Retrospective register study utilizing data from 2020-2022.
  • Data sources included patient safety incident reports, nurse scheduling, and hospital information systems.
  • Nurse-to-patient ratios (NPR) were categorized (0.33:1, 0.75:1, 1:1, 1.5:1) based on patient care intensity per shift.

Main Results:

  • A total of 382 AEs were reported during the study period.
  • Most AEs occurred during understaffed (61%) or overstaffed (29.8%) periods.
  • AEs were also frequent during shift overlaps (26%) and morning shifts (49%).
  • Significant differences in patient distribution were observed during AEs in intensive care (P=0.0013) and high maintenance intensive care (P<0.0001).

Conclusions:

  • Both understaffing and overstaffing significantly increase the risk of adverse events in the NICU.
  • Achieving an optimal nurse-to-patient ratio is vital for preventing AEs and enhancing patient safety.
  • Regular review of AE reports can identify unit-specific risks (e.g., shift overlaps, high-risk shifts) to inform effective staffing and improve care quality.