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Decision making in chronic subdural haematoma patient referrals in an octogenarian and nonagenarian population - a
Joshua MacArthur1, Sayan Biswas2, Lareyna McMenemy1
1Faculty of Biology, Medicine and Health, University of Manchester, Manchester, Greater Manchester, UK.
Insights
Chronic subdural haematoma (CSDH) referral acceptance is lower in the very elderly. CSDH size and premorbid quality of life (QoL) are key predictors for neurosurgical intervention in all age groups.
Area of Science:
- Neurosurgery
- Geriatric Medicine
- Public Health
Background:
- Chronic subdural haematoma (CSDH) incidence is increasing among the elderly population.
- Limited research exists on CSDH management in patients over 80.
- Referral acceptance by tertiary centers dictates neurosurgical intervention in the UK.
Purpose of the Study:
- To identify predictors of neurosurgical referral acceptance for chronic subdural haematoma (CSDH) in octogenarian and nonagenarian patients.
- To compare referral acceptance predictors between ultra-elderly (≥80 years) and adult (<80 years) populations.
- To analyze the influence of age, clinical presentation, CSDH characteristics, and premorbid quality of life (QoL) on referral acceptance.
Main Methods:
- A multi-center retrospective case series analysis (January 2015 - May 2020).
- Patients categorized as adult (<80 years) or ultra-geriatric (≥80 years), with further subgrouping into octogenarians (80-89) and nonagenarians (≥90).
- Multivariable logistic regression utilized to assess predictors including age, headache, dementia, motor weakness, midline shift, CSDH size, and premorbid QoL.
Main Results:
- Referral acceptance was significantly lower in ultra-geriatric patients (22.4%) compared to adults (38.1%) and in nonagenarians (10.5%) versus octogenarians (27.7%).
- CSDH size and premorbid QoL were consistent independent predictors of acceptance across all age groups.
- Predictor significance varied by age group; in nonagenarians, only age, CSDH size, and QoL were significant.
Conclusions:
- CSDH size and premorbid QoL are crucial independent predictors for neurosurgical referral acceptance in all age groups.
- These factors are particularly important for the octogenarian and nonagenarian populations.
- Other clinical variables demonstrate age-dependent significance in predicting referral acceptance for CSDH management.
Background:
The incidence of chronic subdural haematoma (CSDH) is rising in the elderly, yet there is limited research focusing on patients aged > 80. In the United Kingdom, the decision to transfer for neurosurgical intervention is dependent upon the acceptance of a CSDH management referral by a tertiary centre.
Aims:
This study thus aims to identify key predictors of referral acceptance in octogenarian and nonagenarian age groups, in comparison to the adult population.
Methods:
A multi-centre retrospective case series analysis from January 2015 to May 2020 was conducted. Patients were grouped as < 80 ('adult') or > 80 ('ultra-geriatric'), with the latter further subgrouped into 80-89 ('octogenarian'), and ≥ 90 ('nonagenarian'). Multivariable logistic regression assessed age, headache, dementia, motor weakness, midline shift, CSDH size, and premorbid quality of life (QoL) to determine predictors of referral acceptance.
Results:
With a total of 3002 patient referrals, referral acceptance was significantly higher in adults compared to the ultra-geriatric group (38.1%vs22.4%, p < 0.001) and in octogenarians versus nonagenarians (27.7%vs10.5%, p = 0.036). CSDH size and premorbid QoL were consistent independent predictors across all age groups. In adults, all seven variables were significant predictors. For the ultra-geriatric group, all but headache and dementia were significant. Among octogenarians, motor weakness, midline shift, CSDH size, and premorbid QoL predicted acceptance, while in nonagenarians, only age, CSDH size, and QoL were significant.
Conclusions:
We demonstrate the importance of CSDH size and premorbid QoL as independent predictor variables for neurosurgical referral acceptance in all analysed age groups, particularly in the octogenarian and nonagenarian patient population, whilst other variables had variable significance depending upon age group.
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