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Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
Published on: March 3, 2023
Visual evoked potentials to a diamond pattern can predict accommodation power more accurately than those to a
Ryota Yamamoto1,2, Shozo Tobimatsu2, Kiyoka Miyahara2,3
1Department of Ophthalmology, Faculty of Medicine, Saga University Hospital, Saga, Japan.
Plos One
|May 14, 2026
Summary
Visual evoked potentials (VEPs) can objectively measure refractive power. Diamond pattern VEPs more accurately predict objective accommodation (OA) than checkerboard patterns, suggesting VEPs can serve as an objective index for refractive error assessment.
Area of Science:
- Ophthalmology
- Neuroscience
- Vision Science
Background:
- Visual evoked potentials (VEPs) reflect visual pathway function.
- Stimulus characteristics like spatial frequency and orientation significantly impact VEPs.
- Objective accommodation (OA) measurement is crucial for understanding visual responses.
Purpose of the Study:
- To investigate the influence of retinal blur on VEPs.
- To determine if VEPs can serve as an objective index for accommodation.
- To compare the efficacy of different visual stimuli in assessing refractive power via VEPs.
Main Methods:
- VEPs were recorded from 21 students using checkerboard (Check) and rotated checkerboard (Diamond) stimuli.
- Objective accommodation (OA) was measured using concave-lens loading.
- Subjective accommodation (SA) was determined using a near-point meter.
- Linear regression analyzed the relationship between SA and OA.
Main Results:
- VEP P100 amplitudes were sensitive to refractive power changes.
- Diamond pattern VEPs provided a more precise prediction of OA compared to Check patterns.
- Significant positive correlations were found between SA and OA for both stimuli, with Diamond showing a stronger correlation.
Conclusions:
- VEPs, particularly with the Diamond stimulus, show promise as an objective measure of refractive power.
- The orientation of visual stimuli influences VEP susceptibility to blur, indicating an orientation effect.
- Discrepancies between subjective and objective accommodation measurements highlight methodological differences.
