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Updated: May 16, 2026

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection
05:31

Studying Cryptosporidium Infection in 3D Tissue-derived Human Organoid Culture Systems by Microinjection

Published on: September 14, 2019

Cryptosporidium secreted proteins form a complex layered interface with the host cell.

Annet Puthenpurackal1, Sandra Moreno Sanchez1, Tifany Schaer1

  • 1Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Plos Pathogens
|May 14, 2026
PubMed
Summary

Cryptosporidium parvum infection is reduced when the dense granule protein DG8 is absent. DG8 forms a crucial ring structure at the host-parasite interface, essential for parasite survival and infection.

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