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Updated: May 16, 2026

Protocol for Isolation of Primary Human Hepatocytes and Corresponding Major Populations of Non-parenchymal Liver Cells
Published on: March 30, 2016
A call for sharing individual patient data from trials in hepatology
Peter Jepsen1, Hugh Watson2, Hendrik Vilstrup3
1Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
None:
Randomised trials provide the strongest evidence to guide clinical care and typically generate detailed data on large numbers of patients. These individual patient data (IPD) should be used to their full potential, including for research questions beyond the original trial objectives. To achieve this, IPD must be shared with other researchers. In this article, we review the history of IPD sharing, report past and current proportions of hepatology trials declaring their willingness to share IPD, and present our own experience of reusing IPD from hepatology trials.
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