Related Experiment Videos
Cerebellar Abscess Caused by Rare Bacteria: A Case Report
Marianna E Kapsetaki1, Christopher Susanto2, Athanasios Theofanopoulos3
1Department of Neurosurgery, University Hospital of Heraklion, Crete, Greece; School of Medicine, University of Crete, Heraklion, Crete, Greece.
Journal of Endodontics
|May 14, 2026
Summary
This study reports a rare case of a cerebellar abscess caused by Rothia dentocariosa and Streptococcus intermedius. The patient recovered after surgery and antibiotics, highlighting a unique brain infection scenario.
Area of Science:
- Neuroscience
- Infectious Diseases
- Microbiology
Background:
- Rothia dentocariosa and Streptococcus intermedius are common upper respiratory tract bacteria.
- Brain abscesses caused by Rothia dentocariosa are exceptionally rare, with only three prior reported cases.
Purpose of the Study:
- To present a rare case of a cerebellar abscess involving both Rothia dentocariosa and Streptococcus intermedius.
- To detail the clinical presentation, diagnostic findings, and management of this unusual brain infection.
Main Methods:
- Case report of a 66-year-old male patient.
- Clinical examination, Magnetic Resonance Imaging (MRI), and Computed Tomography (CT) brain scans.
- Surgical intervention (unilateral suboccipital craniectomy and drainage) and microbiological cultures.
- Intravenous antibiotic therapy.
Main Results:
- The patient presented with neurological deficits including dizziness, imbalance, and diplopia, indicative of cerebellar dysfunction.
- Imaging revealed a cerebellar lesion with significant surrounding edema, which worsened despite initial management.
- Cultures confirmed the presence of Rothia dentocariosa and Streptococcus intermedius as the causative agents of the abscess.
- The patient showed gradual clinical improvement following surgical drainage and a course of antibiotics.
Conclusions:
- This case represents a rare instance of a cerebellar abscess caused by the synergistic infection of Rothia dentocariosa and Streptococcus intermedius.
- The findings underscore the importance of considering unusual microbial pathogens in brain abscesses, even in the absence of a clear infectious source.
- Successful management involved a combination of surgical intervention and targeted antibiotic therapy.
Related Concept Videos
Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Viral Meningitis
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Bacterial Meningitis II: Pathophysiology
Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Atypical Pneumonia
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...