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Sensitization to 19 allergen sources in 2,124 children in Kashi Prefecture, China: a single-center cross-sectional

Riziwanguli Maitusong1, Asimuguli Wubuli1, Ayiguli Saimaier1

  • 1The Second Department of Pediatric Internal Medicine, The First People's Hospital of Kashi, Kashi, Xinjiang, China.

Frontiers in Allergy
|May 15, 2026
PubMed

Insights

Allergen sensitization is common in Kashi children, with inhalant and food allergens frequently detected. Identifying specific allergens through serum-specific IgE (sIgE) testing is key for preventing allergic diseases.

Area of Science:

  • Pediatric Allergy and Immunology
  • Environmental Health
  • Immunology

Background:

  • Allergic diseases pose a significant health burden in children.
  • Understanding regional allergen sensitization patterns is crucial for targeted prevention strategies.
  • Kashi Prefecture's specific demographic requires investigation into common allergen sensitivities.

Purpose of the Study:

  • To determine the prevalence of sensitization to common allergens in children in Kashi Prefecture.
  • To identify the most frequent allergen sources contributing to sensitization.
  • To provide a scientific basis for the prevention of allergic diseases in this population.

Main Methods:

  • Retrospective analysis of serum allergen-specific IgE (sIgE) antibody detection results.
  • Data collected from 2,124 children at the First People's Hospital of Kashi Prefecture.
  • Study period spanned from January 2022 to December 2024.

Main Results:

  • Overall sIgE sensitization rate was 42.70%.
  • Inhalant allergens showed a 29.52% sensitization rate, with tree combinations, cat fur, and Artemisia argyi being most common.
  • Food allergens had a 24.01% sensitization rate, with egg whites, milk, and peanuts being most frequent. Sensitization varied by sex, age, and season.

Conclusions:

  • Common allergen sensitization is prevalent in Kashi children, often asymptomatic.
  • Sensitization patterns differ significantly based on sex, age, and season.
  • sIgE testing is valuable for identifying specific allergen triggers, aiding in allergic disease prevention.
Abstract

Keywords:
Kashi Prefectureallergic diseaseschildimmunoglobulin Esensitization

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