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Benchmarking Surgical Outcomes for Endoscopic Transnasal Craniopharyngioma Resection: Implications for Clinical
Samuel A Tenhoeve1,2, Cody Orton1,2, Diwas Gautam1,2
1Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City, Utah, USA.
Operative Neurosurgery (Hagerstown, Md.)
|May 15, 2026
Summary
This study establishes surgical outcome benchmarks for endoscopic craniopharyngioma resection in adults. These benchmarks aid in assessing performance and guiding clinical decisions for improved patient care.
Area of Science:
- Neurosurgery
- Oncology
- Endocrinology
Background:
- Craniopharyngiomas are complex intracranial tumors with challenging surgical management.
- Endoscopic resection is a key surgical approach for these tumors.
Purpose of the Study:
- To develop risk-stratified surgical outcome benchmarks for adult patients undergoing endoscopic craniopharyngioma resection.
- To facilitate cross-institutional comparisons and guide clinical decision-making.
Main Methods:
- Retrospective analysis of 318 adult patients from 14 US academic centers (2011-2024).
- Patients stratified into low-risk and high-risk cohorts based on clinical and tumor characteristics.
- Surgical outcomes analyzed to define benchmarking ranges using established methodology.
Main Results:
- Benchmarking analysis identified ranges for length of stay, readmission, discharge to skilled nursing facility, CSF leak, gross total resection, VAsopressin deficiency, and tumor progression.
- Low-risk patients (n=136) showed specific outcome ranges, e.g., 4.0-6.0 days length of stay, 15.5%-22.2% 90-day readmission.
- Proposed benchmark ranges facilitate cross-institutional comparisons.
Conclusions:
- Established surgical outcome benchmarks provide a framework for assessing performance in endoscopic craniopharyngioma resection.
- Benchmarks can inform quality improvement, risk stratification, and patient counseling.
- Data from the Registry of Adenomas of the Pituitary and Related Disorders database was crucial for this analysis.
