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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
Fungal Phylum Basidiomycota01:26

Fungal Phylum Basidiomycota

Basidiomycota is a diverse phylum of fungi that includes ecologically significant decomposers such as white rot fungi, symbionts like mycorrhizal fungi, plant pathogens such as rusts and smuts, and edible species like Agaricus bisporus (the common button mushroom). These fungi play crucial roles in nutrient cycling, symbiotic relationships, and even human health. Their defining feature is the basidium, a microscopic club-shaped structure responsible for producing basidiospores.Fruiting Bodies...

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Related Experiment Video

Updated: May 17, 2026

Isolation, Behavioral Identification, and Pathogenicity Assessment of Entomopathogenic Fungi from a Forest Wood Borer
06:58

Isolation, Behavioral Identification, and Pathogenicity Assessment of Entomopathogenic Fungi from a Forest Wood Borer

Published on: September 29, 2023

Mycetoma.

Max Hoekstra1, Kirby R Lattwein1, Wendy W J van de Sande1

  • 1Department of Medical Microbiology & Infectious Diseases, ErasmusMC, Rotterdam, The Netherlands.

Plos Neglected Tropical Diseases
|May 15, 2026
PubMed
Summary

Mycetoma, a neglected tropical disease, causes tumor-like masses due to bacterial or fungal infections, particularly affecting male farmers in low-income regions. Further research is crucial to address significant knowledge gaps in its management.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Epidemiology

Background:

  • Mycetoma is a chronic, progressive neglected tropical disease causing subcutaneous tumor-like masses.
  • It is endemic in rural, low- and middle-income countries, disproportionately affecting male farmers.
  • Caused by bacteria (actinomycetoma) or fungi (eumycetoma), it forms grains resistant to treatment.

Purpose of the Study:

  • To review current knowledge on mycetoma.
  • To cover historical background, epidemiology, causative agents, pathophysiology, diagnosis, treatment, and prevention.
  • To highlight remaining knowledge gaps and future research directions.

Main Methods:

  • Comprehensive literature review.
  • Synthesis of existing data on mycetoma.

Related Experiment Videos

Last Updated: May 17, 2026

Isolation, Behavioral Identification, and Pathogenicity Assessment of Entomopathogenic Fungi from a Forest Wood Borer
06:58

Isolation, Behavioral Identification, and Pathogenicity Assessment of Entomopathogenic Fungi from a Forest Wood Borer

Published on: September 29, 2023

  • Analysis of historical and current research findings.

    • Main Results:

    • Mycetoma presents significant health and socioeconomic burdens.
    • Inoculation occurs via skin breaches, with pathogens forming resistant grains.
    • Despite increased awareness, substantial knowledge gaps persist.

    Conclusions:

    • Mycetoma requires further research and improved management strategies.
    • Understanding causative agents and pathophysiology is key.
    • Addressing knowledge gaps is essential for effective disease control.