Cervical pathology: Diagnosis, treatment and management of patients with Human Papillomavirus

Aim: The objective of this literature review was to identify current aspects of the diagnosis, treatment, and management of patients with human papillomavirus.

Materials and Methods: 15 articles published from 2018 to 2024 were analyzed using the keywords: cervix, Papillomavirus, precancerous cervical pathology, cervical cancer, cervical screening, cytological method, colposcopy, cervical biopsy, for which a review of the available literature was conducted. Pubmed, Google Scholar, Web of Science, and Scopus databases were used to search for materials on current aspects of the diagnosis, treatment and management of patients with Human Papillomavirus. Inclusion criteria were cervical pathology caused by human papillomavirus.

Conclusions: The goal of the screening program is to detect and treat high-grade precancer and prevent the development of cancer. Detection of LSIL (CIN1) is carried out by HPV testing and cervical screening, and the diagnosis is verified by histology. Most guidelines talk about surveillance from 18 years of age for 2 years for CIN 1. Diagnosis of persistent infection with HPV 16, 18, 31, 33 and others, and not the presence of CIN1, determines the risk of developing CIN 3.