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Assessing the Feasibility of Community-Based Colorectal Cancer Screening in Pune, India
Smita Joshi1, Parimal Lawate2, B Kishore Kumar3
1Prayas, Amrita Clinic, Pune, India.
Cancer Research Communications
|May 15, 2026
Summary
This study screened 4352 individuals for colorectal cancer (CRC) using fecal occult blood tests. While CRC and polyp detection rates were low, the findings emphasize the need for preventive healthcare investment in India.
Area of Science:
- Gastroenterology
- Public Health
- Oncology
Background:
- Colorectal cancer (CRC) incidence and mortality are rising in India despite lower rates compared to Southeast Asian countries.
- Community-based screening is crucial for early detection and management of CRC.
Purpose of the Study:
- To report the outcomes of a large-scale, community-based CRC screening project in India.
- To assess the feasibility and yield of fecal occult blood testing (FOBT) followed by colonoscopy.
Main Methods:
- A house-to-house survey screened 5003 consenting adults aged 50-75 years.
- Participants provided stool samples for immunochemical fecal occult blood testing (iFOBT) using CANCHECK-FOBT.
- Positive iFOBT results prompted outpatient colonoscopy for further investigation.
Main Results:
- Out of 4352 participants who provided samples, 1.61% (70) had positive iFOBT results.
- Colonoscopy was completed by 44.92% (31) of those with positive iFOBT.
- The study detected 0.23 cases of CRC and 1.15 adenomatous polyps per 1000 screened individuals.
Conclusions:
- The CRC and adenomatous polyp detection rates were lower than in neighboring Southeast Asian countries.
- These results underscore the importance of investing in preventive healthcare strategies for CRC in India.
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