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Related Concept Videos

Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Biological Effects of Radiation02:59

Biological Effects of Radiation

All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they produce ions...
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...

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Related Experiment Video

Updated: May 17, 2026

Radiosensitivity of Cancer Stem Cells in Lung Cancer Cell Lines
09:45

Radiosensitivity of Cancer Stem Cells in Lung Cancer Cell Lines

Published on: August 21, 2019

Radon and lung cancer.

Edouard Auclin1, Maxime Janin2, Laura Mezquita3

  • 1Hôpital Européen Georges Pompidou, Assistance Publique des Hôpitaux de Paris, Paris, France; Institut Bergonié, Bordeaux, France.

Bulletin Du Cancer
|May 15, 2026
PubMed
Summary

Radon, a radioactive gas in homes, significantly increases lung cancer risk, especially when combined with smoking. Reducing indoor radon through ventilation and measurement is crucial for prevention.

Keywords:
Lung adenocarcinomaLung cancerRadon

Related Experiment Videos

Last Updated: May 17, 2026

Radiosensitivity of Cancer Stem Cells in Lung Cancer Cell Lines
09:45

Radiosensitivity of Cancer Stem Cells in Lung Cancer Cell Lines

Published on: August 21, 2019

Area of Science:

  • Environmental Health
  • Oncology
  • Radiological Science

Background:

  • Lung cancer is a leading global cause of death, with tobacco as the primary risk factor.
  • Other significant risk factors include occupational exposures, air pollution, and indoor radon gas.
  • Radon, a naturally occurring radioactive gas from uranium decay, accumulates in buildings and is a major contributor to lung cancer.

Purpose of the Study:

  • To elucidate the mechanisms by which radon exposure contributes to lung carcinogenesis.
  • To quantify the association between radon exposure levels and lung cancer risk.
  • To explore the synergistic effects of radon and smoking on lung cancer development.

Main Methods:

  • Review of epidemiological studies investigating radon exposure and lung cancer incidence.
  • Analysis of biological mechanisms including genomic damage and immune system alterations.
  • Examination of current prevention strategies and regulatory frameworks for indoor radon.

Main Results:

  • Radon exposure is independently linked to increased lung cancer risk, with a 10-20% rise per 100Bq/m³ increment.
  • Radon's risk is synergistic with smoking, amplifying the combined carcinogenic effect.
  • Radon exposure induces DNA mutations, breaks, and immune dysfunction, promoting tumor development.

Conclusions:

  • Indoor radon is a significant, preventable environmental risk factor for lung cancer.
  • Effective prevention requires improved building ventilation, sealing, and widespread radon monitoring.
  • Further research, like prospective studies, is needed to refine understanding and screening strategies for radon-induced lung cancer.