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Related Experiment Video

Updated: May 17, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

Symptom Networks in Postsurgical Cancer Pain Across Recovery Stages.

Jian Zhao1, Kristin L Schreiber2, Jenson Kaithamattam3

  • 1Department of Supportive Oncology, Dana-Farber Cancer Institute, Boston, MA.

Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses
|May 15, 2026
PubMed
Summary
This summary is machine-generated.

Cancer patients’ pain and psychological distress differ based on time since surgery. Early recovery prioritizes helplessness and sleep disturbance, while later recovery focuses on pain interference management.

Keywords:
CancerNetwork analysisPain catastrophizing scalePostsurgical painSleep disturbance

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An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
14:56

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Published on: January 27, 2010

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Last Updated: May 17, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)

Published on: January 27, 2010

Area of Science:

  • Oncology
  • Pain Management
  • Psychological distress

Background:

  • Pain is a primary reason for emergency department visits in cancer patients.
  • Psychological distress frequently exacerbates cancer pain.
  • Understanding symptom dynamics across postoperative stages is crucial for personalized management.

Purpose of the Study:

  • To analyze symptom interconnections in cancer patients based on their surgical history (recent vs. distant).
  • To map symptom networks using network analysis to identify stage-specific symptom management targets.

Main Methods:

  • Secondary analysis of a prospective observational cohort study.
  • Patient-reported outcomes included pain severity, pain interference, anxiety, depression, sleep disturbance, and pain catastrophizing.
  • Network analysis and comparison were used to examine symptom interconnections.

Main Results:

  • No significant global differences were found between recent (≤3 months) and distant (>3 months) postoperative networks.
  • Helplessness and sleep disturbance were prominent in the recent group.
  • Pain interference acted as a key bridge between pain and psychological symptoms in the distant group.

Conclusions:

  • Symptom networks reveal distinct patterns in early versus late postoperative cancer recovery.
  • Helplessness and sleep disturbance are early priorities, while pain interference is a later target.
  • Findings support stage-specific screening and interventions for cancer patients experiencing pain and psychological distress.