Effectiveness of a digital communication and active recall strategy to improve pediatric influenza vaccination in

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Antonio Di Mauro1, Ilaria Farella2, Mariano Manzionna3

  • 1Pediatric Primary Care, National Pediatric Health Care System, LHU BA, Bari, Italy.

BMC Public Health
|May 15, 2026
PubMed

Insights

A digital and active reminder intervention significantly boosted pediatric influenza vaccination rates, achieving 47.4% coverage and demonstrating 85% vaccine effectiveness against confirmed influenza cases.

Area of Science:

  • Pediatric Public Health
  • Vaccinology
  • Digital Health Interventions

Background:

  • Influenza poses a significant health risk to young children, with suboptimal influenza vaccination uptake.
  • Existing vaccination programs require innovative strategies to improve coverage rates in pediatric populations.

Purpose of the Study:

  • To evaluate the effectiveness of a combined digital and active reminder intervention for increasing influenza vaccination coverage in children aged 6 months to 6 years.
  • To assess the impact of the intervention on influenza-like illness (ILI) incidence and confirmed influenza cases.

Main Methods:

  • A prospective observational study involved 792 children (6 months to 6 years) in a pediatric primary care setting.
  • Parents received web-based educational content and personalized reminders regarding influenza vaccination.
  • Vaccination coverage, ILI episodes, and confirmed influenza cases were monitored.

Main Results:

  • The intervention achieved 47.4% vaccination coverage, significantly higher than local (33.1%) and regional (29.7%) benchmarks.
  • Vaccinated children exhibited a significantly lower incidence of ILI and confirmed influenza compared to unvaccinated children (p < 0.001).
  • The calculated vaccine effectiveness against influenza was 85%.

Conclusions:

  • The combined digital and active reminder intervention effectively improved pediatric influenza vaccination coverage.
  • The intervention demonstrated a significant reduction in ILI and confirmed influenza cases among vaccinated children.
  • Digital strategies show promise for enhancing the success of pediatric influenza vaccination programs.
Abstract

Keywords:
Active recallDigital health toolsInfluenza vaccinationPediatric primary careReminder systemsSocial media

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