Related Experiment Video
Updated: May 17, 2026
![[(DPEPhos)(bcp)Cu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[(DPEPhos)(bcp)Cu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
3d Transition Metals-Catalyzed Electrooxidative and Photoredox Asymmetric CH Activation: A Sustainable Futuristic
Sarthi1,2, Tamanna Sharma1,2, Aadarsh Shrivastav1,2
1Chemical Technology Division, CSIR-Institute of Himalayan Bioresource and Technology, Palampur, India.
Abstract:
3d transition metal (TM)-catalyzed asymmetric CH activation has developed as an efficacious and powerful strategy for direct synthesis of chiral organic molecules. In recent years, electrooxidative and photoredox approaches have been coupled with 3d TM-catalyzed asymmetric CH activation to fully realize the sustainable potential of this protocol. Herein, we highlight the comprehensive account of recent advancements within the realm of asymmetric CH activation, focusing on sustainability with special emphasis on 3d metal catalysts and the strategies that incorporate electrooxidative and photoredox approaches. This review also aims to foster a greater understanding of fundamental catalytic processes in sustainable metallaelectro and photoredox strategies for the synthesis of enantiopure scaffolds.
Related Concept Videos
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Cycloaddition Reactions: MO Requirements for Photochemical Activation
Thermal and Photochemical Electrocyclic Reactions: Overview
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
Thermal Electrocyclic Reactions: Stereochemistry
Selection Rules: Thermal Activation
Conjugated systems containing an even number of π-electron pairs undergo a conrotatory ring closure. For example, thermal electrocyclization of (2E,4E)-2,4-hexadiene, a conjugated diene containing two π-electron pairs, gives trans-3,4-dimethylcyclobutene.
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide

