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Hemoglobinuria associated with Candidatus Mycoplasma Haemobos in a primiparous Holstein cow in Turkey: a case report
Fikri Emlik1, Hüsnü Furkan Şakar2, Sefer Türk3
1Department of Internal Medicine, Faculty of Veterinary Medicine, Sivas Cumhuriyet University, Sivas, Turkey. fikriemlik@cumhuriyet.edu.tr.
Abstract:
Bovine hemoplasmas, including Mycoplasma wenyonii (M. wenyonii) and Candidatus Mycoplasma haemobos (C. M. haemobos), are vector-borne pathogens that can cause significant clinical diseases in cattle. This case report from Türkiye describes the clinical findings, hematological analysis, and serum biochemistry results of a cow presenting with hemoglobinuria caused by C. M. haemobos. Blood samples from the infected animal were analyzed using hematological, biochemical, microscopic, and molecular methods. Multiplex polymerase chain reaction assay confirmed the infection, and microscopic analysis revealed a parasitemia rate of 6.99%. Clinical signs included hemoglobinuria, icterus, and anemia. The treatment included fluid therapy, antibiotic (oxytetracycline), and antianemic drugs. The cattle died 1 month post-treatment, reportedly due to a lower respiratory tract infection. This case report describes the diagnostic methods, clinical findings, and laboratory results. A widescale molecular survey of C. M. haemobos in cattle is warranted, with investigation of its pathogenicity and pathogenies.
Insights
Candidatus Mycoplasma haemobos caused severe anemia and hemoglobinuria in a Turkish cow. Diagnosis involved molecular and microscopic methods, but the animal succumbed to a secondary respiratory infection despite treatment.
Area of Science:
- Veterinary Medicine
- Microbiology
- Pathogen Research
Background:
- Bovine hemoplasmas like Mycoplasma wenyonii and Candidatus Mycoplasma haemobos are significant tick-borne cattle pathogens.
- These infections can lead to severe clinical manifestations and economic losses in livestock.
Purpose of the Study:
- To report a case of hemoglobinuria in a cow caused by Candidatus Mycoplasma haemobos.
- To detail the diagnostic approaches, clinical signs, and laboratory findings associated with this infection.
Main Methods:
- Hematological, biochemical, microscopic, and molecular analyses were performed on blood samples.
- Multiplex polymerase chain reaction (PCR) was used for pathogen identification.
- Parasitemia was quantified via microscopic examination.
Main Results:
- The cow presented with clinical signs of hemoglobinuria, icterus, and anemia.
- Multiplex PCR confirmed Candidatus Mycoplasma haemobos infection.
- Microscopic analysis showed a parasitemia rate of 6.99%.
Conclusions:
- Candidatus Mycoplasma haemobos can cause severe clinical disease in cattle, including hemoglobinuria and anemia.
- Prompt diagnosis using integrated methods is crucial.
- Further molecular surveys and pathogenicity studies are recommended to understand the impact of Candidatus Mycoplasma haemobos in cattle populations.
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