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A Nonviral Approach to Generate Transient Chimeric Antigen Receptor T Cells Using mRNA for Cancer Immunotherapy
Published on: February 21, 2025
Prior Malignancy History and Risk of Second Malignancies After Allogeneic Hematopoietic Cell Transplantation
Nihar Desai1, Eshrak Al-Shaibani1, Tommy Alfaro-Moya1
1Hans Messner Allogeneic Transplant Program, Division of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto, Canada; Temerty Faculty of Medicine, University of Toronto, Toronto, Canada.
Transplantation and Cellular Therapy
|May 16, 2026
Abstract
No abstract available in PubMed .
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Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Cell-mediated Immune Responses
Overview
