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Published on: February 24, 2023

Melioidosis: diverse clinical manifestations and patient outcomes in a case series

Ravi Kishor Allu1, Raviteja Nalabothula1, Kamala Kannan1

  • 1SRM Medical College Hospital and Research Centre, Department of General Medicine, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu, Tamil Nadu, India.

BMC Infectious Diseases
|May 16, 2026
PubMed

Insights

Melioidosis, a complex bacterial disease, presents varied symptoms and is contracted from soil or water. This case series details five patients, aiding understanding of melioidosis diagnosis and treatment.

Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Clinical Medicine

Background:

  • Melioidosis is caused by Burkholderia pseudomallei, a gram-negative bacterium.
  • Transmission occurs through contact with contaminated soil or water.
  • The disease exhibits diverse clinical manifestations.

Purpose of the Study:

  • To present a case series of five melioidosis patients.
  • To highlight diverse clinical presentations, diagnostic challenges, and treatment outcomes.
  • To review current literature on melioidosis epidemiology, pathogenesis, and management.

Main Methods:

  • Case series methodology.
  • Analysis of clinical data from five melioidosis patients.
  • Literature review on melioidosis.

Main Results:

  • Five patients with melioidosis were diagnosed.
  • Diverse clinical presentations were observed.
  • Treatment approaches and outcomes varied.

Conclusions:

  • Melioidosis is a complex disease with variable presentations.
  • Effective diagnosis and management require careful consideration of clinical and epidemiological factors.
  • Further research into melioidosis pathogenesis and treatment is warranted.
Keywords:
BacteremiaIntensive and eradication therapyMelioidosisNeuromelioidosisPneumonia

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