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Updated: May 19, 2026
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Prior Stroke Increases Residual Shunt Risk After Combined Ablation and LAAO: A Device-Specific Interaction.
Haoqing Ren1,2, Hengli Lai2
1Jiangxi Medical College, Nanchang University, Nanchang, China.
The combined catheter ablation and left atrial appendage occlusion procedure is safe and effective for atrial fibrillation patients with prior stroke. However, stroke history increases residual shunt risk, influenced by device choice.
Area of Science:
- Cardiology
- Interventional Cardiology
- Electrophysiology
Background:
- Atrial fibrillation (AF) management often involves catheter ablation (CA) and left atrial appendage occlusion (LAAO).
- The combined
- one-stop
- CA+LAAO
- procedure
- safety
- efficacy
- in
- AF
- patients
- with
- prior
- cerebral
- infarction
- requires
- validation.
Purpose of the Study:
- To evaluate the safety and efficacy of the combined
- one-stop
- CA+LAAO
- procedure
- in
- AF
- patients
- with
- a
- prior
- history
- of
- cerebral
- infarction.
Main Methods:
- Retrospective, single-center study of 242 AF patients undergoing the
- one-stop
- CA+LAAO
- procedure.
Main Results:
- Procedural success and AF recurrence rates were similar between patients with and without prior stroke.
- Patients with prior stroke had a significantly higher incidence of post-procedural residual shunt.
- Device type significantly modified the risk of residual shunt in patients with prior stroke.
Conclusions:
- The
- one-stop
- CA+LAAO
- strategy
- is
- safe
- and
- effective
- for
- AF
- patients
- with
- prior
- stroke.
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