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Published on: November 7, 2020
Risk Factors for Dysfunctional Liver Graft Response: A Case-Control Study.
Layana de Paula Cavalcante1, João Cruz Neto1, Maria Beatriz Freire Alves1
1Federal University of Ceará, Fortaleza, Brazil.
Nursing & Health Sciences
|May 17, 2026
Summary
Identifying risk factors for dysfunctional liver graft response after liver transplantation is crucial. Factors include recipient age, renal function, donor age, and ischemia times, informing nursing care.
Area of Science:
- Transplantation research
- Nephrology
- Surgical nursing
Background:
- Liver transplantation is a complex procedure with potential for graft dysfunction.
- Early identification of risk factors is essential for improving patient outcomes.
- Dysfunctional liver graft response impacts patient survival and quality of life.
Purpose of the Study:
- To identify recipient, donor, and graft-related risk factors for dysfunctional liver graft response.
- To analyze medical records of adult liver transplant recipients using a case-control design.
- To inform the development of nursing diagnoses related to liver graft complications.
Main Methods:
- Case-control study analyzing adult liver transplant recipient medical records.
- Cases defined by early graft dysfunction or death/retransplantation within 6 months.
- Logistic regression analysis to identify significant risk factors.
Main Results:
- Recipient factors: younger age, renal dysfunction, higher BMI, less transfusion.
- Donor factors: older age, male sex, elevated serum sodium.
- Graft factors: prolonged warm and cold ischemia times.
Conclusions:
- Dysfunctional liver graft response is multifactorial, involving recipient, donor, and graft characteristics.
- Findings support the nursing diagnosis 'Risk for Dysfunctional Liver Graft Response'.
- Highlights the importance of nursing care throughout the liver transplantation process.
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