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Premyopia Management in China: From Biometrics to Clinical Management

Lizhen Chen1, Li Sun, Hiu Ying Leung

  • 1The Primasia International Eye Research Institute (PIERI) (H.Y.L., J.Z., D.S.C.L.), School of Medicine, The Chinese University of Hong Kong (Shenzhen), Shenzhen, China; Department of Ophthalmology (L.C., L.S., D.S.C.L.), Zhujiang Hospital, Southern Medical University, Guangzhou, China; Department of Ophthalmology and Visual Sciences (D.S.C.L.), The Chinese University of Hong Kong, Hong Kong, China; Eye Department (L.C., H.Y.L., J.Z., D.S.C.L.), C+ Health CKJ (Shenzhen) Hospital, Shenzhen, China; C-MER (Guangzhou) Dennis Lam Eye Hospital (L.C. L.S.), Guangzhou, China; C-MER (Shenzhen) Dennis Lam Eye Hospital (L.C., H.Y.L., J.Z., D.S.C.L.), Shenzhen, China; and The C-MER Dennis Lam and Partners Eye Center (H.Y.L. D.S.C.L.), C-MER International Eye Care Group, Hong Kong, China.

Eye & Contact Lens
|May 18, 2026
PubMed

Insights

Effective premyopia management in China involves biometric monitoring and interventions like outdoor time and low-concentration atropine. A risk-stratified approach is crucial to combat the rising myopia epidemic in children.

Area of Science:

  • Ophthalmology
  • Public Health
  • Pediatrics

Background:

  • Myopia is a significant global health issue, with increasing prevalence in Chinese children.
  • Premyopia presents a critical window for intervention to prevent myopia progression.

Purpose of the Study:

  • To review evidence on premyopia management strategies in China.
  • To outline a risk-stratified clinical framework for premyopia interventions.

Main Methods:

  • Summarized biometric predictors: hyperopic reserve, axial length (AL), and AL/CR ratio.
  • Reviewed interventions: outdoor time, optical methods, low-concentration atropine (LCA), combination therapy, and red-light therapy.
  • Proposed a clinical management framework integrating biometric data and interventions.

Main Results:

  • Biometric parameters effectively predict myopia risk.
  • Various interventions show promise, but challenges in compliance, safety, and regulation persist.
  • A structured, evidence-based approach is feasible for managing premyopia.

Conclusions:

  • Integrating biometric monitoring with tiered interventions is essential for controlling childhood myopia in China.
  • Addressing challenges is key to successful implementation of premyopia management strategies.

Keywords:
Biometric predictorsHigh-risk premyopiaInsufficient hyperopic reservePremyopiaPremyopia management

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