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Chronic Invasive Fungal Sinusitis Concerning for Sinonasal Malignancy With Unique Intracranial Extension.

Andrew Jung1, Margaret Scott1, Matthew Liu2

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Chronic invasive fungal sinusitis is a rare condition causing inflammation and bone destruction. This case highlights a fungal mass with orbital and intracranial spread, managed with surgery and antifungal therapy.

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Area of Science:

  • Otolaryngology
  • Mycology
  • Neurosurgery

Background:

  • Chronic invasive fungal sinusitis (CIFS) is a rare sinonasal pathology.
  • Characterized by fungal presence, chronic inflammation, bony destruction, and extrasinus invasion.
  • Often presents with complex clinical and radiological findings.

Purpose of the Study:

  • To describe a rare case of CIFS.
  • To detail the management of a fungal mass with orbital and intracranial extension.
  • To emphasize the multidisciplinary approach required for such cases.

Main Methods:

  • Nasal endoscopy with biopsy for diagnosis.
  • Surgical debridement to remove the fungal mass and affected tissue.
  • Postoperative antifungal therapy to eradicate residual fungal infection.

Main Results:

  • Histopathological confirmation of fungal elements causing chronic inflammation.
  • Radiological evidence of bony destruction, orbital involvement, and intracranial extension.
  • Successful management through a combination of surgical and medical interventions.

Conclusions:

  • CIFS requires prompt diagnosis and aggressive management.
  • Multidisciplinary collaboration is crucial for optimal outcomes.
  • Antifungal therapy is essential in the postoperative period.