[Stereotactic radiotherapy of inoperable localized lung cancers]

Stereotactic body radiotherapy (SBRT) is a treatment technique for localized non-small cell lung cancer, primarily used in patients who are inoperable or at high surgical risk. It delivers precise ablative doses in a few sessions, ensuring excellent local control (85-98%) and low toxicity. Efficacy relies on a sufficient biological dose that is tailored to the tumor's location. Various techniques allow for the management of respiratory motion, including the placement of fiducials around the lesion. SBRT is suitable for elderly or frail patients, regardless of their initial lung capacity. It is now the standard of care for early-stage, inoperable lung cancer, combining efficacy, safety, and personalized treatment.