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Propofol-fentanyl versus propofol-dexmedetomidine: Hemodynamics and recovery during supraumbilical surgery
Leena Rohilla1, Ritu Sharma2, Rajeev Lochan Tiwari2
1Department of Anaesthesia, Maharishi Chyawan Medical College, Koriawas Narnaul, Haryana, India.
Abstract:
Propofol requires adjuncts for balanced anaesthesia due to cardiovascular depression and lack of analgesia. Dexmedetomidine offers superior sympatholysis versus opioids like fentanyl but risks delayed recovery. Therefore, it is of interest to compare propofol-fentanyl (PF, n=40) versus propofol-dexmedetomidine (PD, n=40) in 80 ASA I-II adults for elective supra-umbilical surgery. Propofol-dexmedetomidine (PD) better attenuated hemodynamic responses (HR/MAP within 10% baseline) versus 20-25% rises in PF, despite modest recovery delays. PD advances knowledge by optimizing intraoperative stability for supra-umbilical surgery at low early recovery cost.
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