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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
The fluid challenge: Evaluating supportive care in dengue through radiological and clinical markers
Puja Singh1, Neetu Bajaj2, Jyoti Namdev1
1Department of Pathology, Bundelkhand Medical College, Sagar, Madhya Pradesh, India.
Abstract:
Dengue poses significant health risks and its treatment via platelet transfusions is costly and impractical in resource-limited settings. Therefore, it is of interest to explore fluid resuscitation as a viable alternative to support hemodynamic stability and enhance platelet recovery. Strong correlations were noted between radiological findings and laboratory parameters. Remarkably, all patients, even the severely affected, recovered without transfusions, with prognosis influenced by factors such as liver function and capillary leakage. Thus, we show that platelet count does not solely indicate disease severity and effective fluid resuscitation can manage dengue effectively without the need for blood transfusions.
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