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Updated: May 19, 2026

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
Published on: October 14, 2016
Periodontal impact in acute myocardial infarction: A comparative study using Russell's periodontal index
Nidhi Dhakray1, Dushyant Pippal2, Bhavna Jha Kukreja3
1Department of Periodontics and Oral Implantology, Maharana Pratap College of dentistry and research centre, Gwalior, Madhya Pradesh, India.
Abstract:
Acute myocardial infarction (AMI) represents a leading global cause of mortality, with emerging evidence linking periodontal disease to cardiovascular risk through systemic inflammatory pathways. Hence, this comparative cross-sectional study evaluated periodontal status using the Russell Periodontal Index (RPI) in 90 AMI patients versus 90 age- and gender-matched healthy controls. AMI patients exhibited significantly higher mean RPI scores (4.82 ± 1.94) compared to controls (1.76 ± 1.23; p < 0.001), with 71.1% showing moderate-to-severe periodontal disease. Multivariate regression analysis confirmed severe periodontal disease as an independent AMI predictor (OR = 2.89; 95% CI: 1.67-4.98) after adjusting for conventional cardiovascular risk factors. These findings advance cardio-periodontology by establishing oral health assessment as a critical component of comprehensive cardiovascular risk stratification and preventive care.
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