FibroScan grading and metabolic correlates of fatty liver disease

Fatty liver disease is increasingly recognized as a hepatic manifestation of systemic metabolic dysfunction. This cross-sectional study, conducted among 165 adult patients with ultrasonographic evidence of fatty liver disease, evaluated metabolic risk factors and liver involvement using FibroScan for steatosis grading and liver stiffness measurement. The results revealed a high prevalence of metabolic syndrome, insulin resistance, dysglycemia and atherogenic dyslipidemia among participants, with moderate to severe hepatic steatosis being common. FibroScan grades showed a significant association between higher steatosis levels and worsening metabolic profiles, including body composition, glycemic parameters and insulin resistance. Thus, we show FibroScan as a valuable non-invasive tool for identifying patients at increased metabolic and hepatic risk, allowing for early risk stratification and management.