Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Reservoir of Infection

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...

Types of Toxins

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...

Toxicity Testing in Animals

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...

Viral Recombination

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Social marginalisation, environmental degradation and Toxoplasma gondii exposure in urban informal settlements in Brazil.

PLoS neglected tropical diseases·2026

Same author

Cocaine pollution alters the movement and space use of Atlantic salmon (Salmo salar) in a large natural lake.

Current biology : CB·2026

Same author

Activation mechanism of the full-length histidine kinase LvrB from pathogenic Leptospira.

Nature communications·2026

Same author

Collaborative mapping: Perceived environmental risk of leptospirosis in Urban communities in Salvador, Brazil.

PLOS global public health·2026

Same author

Canine seroepidemiology of Trypanosoma cruzi in socially vulnerable urban communities of Salvador, Brazil.

Acta tropica·2026

Same author

Co-production of informal settlement health: a community based participatory research program for building healthy communities in urban informal settlements of Salvador, Brazil.

Frontiers in public health·2026

Same journal

Urban Conflagrations: Structural Ash and Soil Metal(loid) Contamination after California's Eaton and Palisades Fires.

Environmental science & technology letters·2026

Same journal

Scientists' statement on the chemical definition of PFASs.

Environmental science & technology letters·2026

Same journal

Observations of the Gas Phase Composition of the 2024 BioLab Industrial Plume in the Atlanta Metropolitan Area.

Environmental science & technology letters·2026

Same journal

A Model for Dry Deposition of Atmospheric Micro- and Nanoplastic Fibers.

Environmental science & technology letters·2026

Same journal

Bioactivity Classification of 2,649 Per- and Polyfluoroalkyl Substances (PFASs) via Quantitative Structure-Activity Relationships and Molecular Docking to Health-Relevant Proteins.

Environmental science & technology letters·2026

Same journal

Discrepancies Between Personal and Ambient Temperatures at Hourly Scale: Insights from Wearable Sensors and Environmental Modeling.

Environmental science & technology letters·2026

See all related articles

Search research articles

Home
Pharmaceutical Pollutants In Urban Rats Are Linked To Zoonotic Infection Risk.

Home
Pharmaceutical Pollutants In Urban Rats Are Linked To Zoonotic Infection Risk.

Related Experiment Video

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

Pharmaceutical Pollutants in Urban Rats Are Linked to Zoonotic Infection Risk.

Anna Jonsson Sundberg¹, Daniel Cerveny^1,2, Federico Costa^3,4

¹Department of Wildlife, Fish, and Environmental Studies, Swedish University of Agricultural Sciences (SLU), SE-901 83 Umeå, Sweden.

Environmental Science & Technology Letters

|May 18, 2026

View abstract on PubMed

Summary

This summary is machine-generated.

Pharmaceutical pollution impacts wildlife disease. In urban rats, common drug residues like azithromycin and citalopram were linked to altered risks of zoonotic infections, affecting human health.

Keywords:

API disease ecology ecotoxicology leptospirosis zoonosis

More Related Videos

Composition and Distribution Analysis of Bioaerosols Under Different Environmental Conditions

Composition and Distribution Analysis of Bioaerosols Under Different Environmental Conditions

Published on: January 7, 2019

Related Experiment Videos

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

Composition and Distribution Analysis of Bioaerosols Under Different Environmental Conditions

Composition and Distribution Analysis of Bioaerosols Under Different Environmental Conditions

Published on: January 7, 2019

Area of Science:

Environmental Science
Ecotoxicology
Zoonotic Disease Epidemiology

Background:

Pharmaceutical pollution is a global environmental concern affecting wildlife.
The impact of pharmaceutical pollution on wildlife disease, particularly zoonotic infections, is not well understood.

Purpose of the Study:

To investigate the presence of Active Pharmaceutical Ingredients (APIs) in urban rats.
To determine the association between API exposure and zoonotic infections in rats.

Main Methods:

Collected 152 rats (Rattus norvegicus and R. rattus) from urban communities in Salvador, Brazil.
Analyzed rat brain tissue for 97 APIs and common zoonotic pathogens (Leptospira spp., Seoul orthohantavirus, Toxoplasma gondii, Capillaria spp., Angiostrongylus spp.).

Main Results:

APIs were detected in 55.3% of rat brain tissues, confirming uptake in wild terrestrial mammals.
Leptospira infection prevalence was 91% lower in rats with azithromycin.
Citalopram exposure was associated with a 3-fold increase in Capillaria infection risk.

Conclusions:

Environmental APIs in urban rats are linked to variations in zoonotic infection risk.
Pharmaceutical pollution represents a novel pathway influencing urban disease dynamics and potentially impacting public health.