In-Hospital Outcomes and Mortality of Pediatric Asthma Exacerbations in Thailand: A Nationwide Study (2015-2022)

Rattapon Uppala1, Phanthila Sitthikarnkha1, Sirapoom Niamsanit1

  • 1Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Insights

Pediatric asthma hospitalizations in Thailand are common, with a low but significant mortality rate. Fatal outcomes are linked to severe complications, especially in adolescents, emphasizing the need for early intervention.

Area of Science:

  • Pediatric respiratory medicine
  • Epidemiology of childhood asthma
  • In-hospital outcomes research

Background:

  • Asthma is a leading cause of childhood morbidity and mortality globally.
  • Limited national data exists on pediatric asthma exacerbations in Thailand.
  • Understanding in-hospital outcomes is crucial for public health.

Purpose of the Study:

  • To quantify in-hospital outcomes for pediatric asthma exacerbations in Thailand.
  • To identify factors associated with complications and mortality.
  • To inform targeted interventions for high-risk children.

Main Methods:

  • Nationwide retrospective study in Thailand (January 2015 - December 2022).
  • Included pediatric patients (<18 years) hospitalized for asthma exacerbation.
  • Multivariate logistic regression analyzed factors linked to endotracheal intubation.

Main Results:

  • Over 283,000 pediatric asthma admissions were analyzed.
  • 2.3% of admissions required endotracheal intubation, primarily in children under 6.
  • In-hospital mortality was 0.1%, with deaths concentrated in adolescents and those with severe complications.

Conclusions:

  • Pediatric asthma imposes a significant burden on Thai hospitals.
  • While rare, asthma-related mortality is clinically significant.
  • Early recognition and optimized management are key to preventing deaths.
Abstract

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