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Updated: May 19, 2026

Ex vivo Culture of Human Placental Explants for the Study of Viral Transmission Across the Maternal-Fetal Interface
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Preventing Fetal Sequelae: The Importance of Proactive Diagnosis of Parvovirus B19 in Pregnancy

Fatemeh Golshahi1, Behrokh Sahebdel1, Nafiseh Saedi1

  • 1Department of Obstetrics and Gynecology, Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Journal of Obstetrics and Gynaecology of India
|May 18, 2026
PubMed

Parvovirus B19 infection during pregnancy can result in vertical transmission in 17-33% of cases, potentially leading to severe complications such as fetal anemia or hydrops fetalis. Although intrauterine transfusion can improve survival in severe cases, delayed diagnosis often results in fetal loss. Due to nonspecific symptoms, missed diagnoses are likely underreported. This editorial strongly advocates for a broader assessment of all mothers presenting with flu-like symptoms, recent exposure to infected individuals, or suspicious ultrasound findings to facilitate earlier detection. Proactive maternal screening is crucial to improving outcomes and reducing fetal mortality associated with parvovirus B19 infection.

Keywords:
Hydrops fetalisIntrauterine transfusionParvovirusPregnancy

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