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Published on: July 8, 2025
LIVIA: a browser-based tool for assessing and visualizing predicted protein interactions
Ah-Ram Kim1, Norbert Perrimon1,2
1Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
None:
As protein structure prediction tools become widely adopted across biology, there is a growing need for accessible methods to assess and visualize predicted protein-protein interactions (PPIs). Here we present LIVIA (Local Interaction Visualization and Analysis), a browser-based tool that computes local PPI confidence metrics across multiple prediction platforms, identifies predicted interface residues, embeds an interactive Mol* 3D viewer, and generates visualization scripts for ChimeraX and PyMOL. The tool automatically detects prediction formats; all parsing and computation occur locally on the user's machine. LIVIA is freely available at https://flyark.github.io/LIVIA.
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