Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 19, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

NeuroFLAME: A Scalable, Privacy-Preserving Federated Framework for Secure, Reproducible, and Multi-Site Neuroimaging

Dylan Martin¹, Sandeep Panta¹, Ross Kelly¹

¹Tri-Institutional Center for Translational Research in Neuroimaging and Data Science, 55 Park Place, Atlanta, 30303, GA, USA.

Biorxiv : the Preprint Server for Biology

|May 18, 2026

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A qualitative study exploring access to online hearing loss information and support for adults with hearing loss.

Frontiers in digital health·2026

Same author

Examining comorbid and transdiagnostic depression clinical outcomes across anxiety, autism, attention deficit hyperactivity disorder (ADHD), bipolar disorder, depression, and schizotypal personality groups: a novel NeuroMark SPECT approach.

medRxiv : the preprint server for health sciences·2026

Same author

Evidence of Population Fragmentation of the Western European Hedgehog <i>Erinaceus europaeus</i> in Urban Landscapes.

Ecology and evolution·2026

Same author

Enhancing Resident Education in Informed Consent Through Digital Checklists.

The American surgeon·2026

Same author

FUNCTIONAL CONNECTIVITY ALTERATIONS IN MAJOR DEPRESSIVE DISORDER.

bioRxiv : the preprint server for biology·2026

Same author

The 2026 IBD UK Standards of healthcare service design and delivery for adults and children living with Crohn's disease and ulcerative colitis.

BMJ open gastroenterology·2026

Same journal

Whole-Embryo 3D Quantification Reveals Conserved Topological Design and Scaling of Germ Layers in Xenopus.

bioRxiv : the preprint server for biology·2026

Same journal

scRNA-seq and genomics analyses reveal key mechanisms of inverted papilloma-associated sinonasal squamous cell carcinoma malignant transformation.

bioRxiv : the preprint server for biology·2026

Same journal

M1C IS NECESSARY FOR DARAXONRASIB RESISTANCE OF NSCLC KRAS(G12C) MUTANT CELLS.

bioRxiv : the preprint server for biology·2026

Same journal

A human-specific genetic modifier reconfigures large-scale cortical network dynamics underlying behavioral performance.

bioRxiv : the preprint server for biology·2026

Same journal

<i>Staphylococcus aureus</i> uses a eukaryotic-like uridyltransferase to make UDP-GlcNAc for cell wall synthesis.

bioRxiv : the preprint server for biology·2026

Same journal

Dynamic redistribution of eIF4F controls cap-dependent translation initiation.

bioRxiv : the preprint server for biology·2026

See all related articles

This summary is machine-generated.

NeuroFLAME enables secure, multi-site neuroimaging research through federated analysis. This open-source platform bridges the gap between experimental federated learning (FL) and real-world clinical applications, ensuring data privacy and consistent results.

Area of Science:

Neuroimaging
Computer Science
Data Privacy

Background:

Federated analysis facilitates multi-site neuroimaging collaboration without raw data sharing.
Current federated healthcare studies are often proofs-of-concept, facing regulatory and security challenges in real-world settings.

Purpose of the Study:

Introduce NeuroFLAME, an enterprise-grade, open-source platform for federated neuroimaging.
Address barriers to real-world implementation of federated learning in neuroimaging research.

Main Methods:

NeuroFLAME is built on NVIDIA FLARE (NVFlare) with outbound communication restriction and a GUI for neuroscientists.
Employs certificate-based trust and containerized execution for reproducible, privacy-preserving analyses.
Demonstrated utility via decentralized guided joint ICA and federated label-based dimensional prediction.

More Related Videos

3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol

3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol

Published on: May 12, 2019

Related Experiment Videos

Last Updated: May 19, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol

3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol

Published on: May 12, 2019

Main Results:

Federated analysis using NeuroFLAME achieved high consistency with centralized approaches.
The platform effectively supports privacy-preserving, reproducible neuroimaging analyses across multiple sites.

Conclusions:

NeuroFLAME bridges the gap between experimental federated learning prototypes and production-ready collaborative tools.
The platform facilitates large-scale, secure neuroimaging research by overcoming implementation barriers.