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Updated: May 19, 2026

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
Published on: May 25, 2018
Reconstructing the complex architecture of the genome with molecular scissors: applying genome editing technology in
Md Nur Amin Khan1, Rohit Das1, Pooja Barik1
1Department of Biopharmaceuticals, National Institute of Pharmaceutical Education and Research Kolkata (NIPER Kolkata), Kolkata, India.
Abstract:
Our past, present, and future are governed by the grand design of the genetic blueprint, which was mapped more than two decades back. While the eloquent design of our genome results from millions of years of evolution and has reached a near-perfect stage, unwanted flaws and mistakes in individual genomes can make their life miserable and worth intervention. The advent of technologies to manipulate the grand design and make it congenial for the individual has given new hope. Here, we discuss how gene editing technologies have progressed and how some of the technologies have become indispensable gears in precision medicine.
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