Fibrous hamartoma of infancy with a rare pseudoangiomatous pattern: A case report

Fibrous hamartoma of infancy (FHI) is a rare benign mesenchymal tumor typically presenting with a triphasic histologic pattern. We report an unusual case of FHI presenting as a breast mass in a 6-month-old infant, characterized by a predominant pseudoangiomatous pattern. Diagnosis was confirmed through clinical, radiologic, and histopathologic correlation, supported by the identification of a specific epidermal growth factor receptor exon 20 mutation. This case highlights the importance of molecular analysis in distinguishing atypical FHI variants from other pediatric tumors.