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Updated: May 19, 2026

Process Development for the Spray-Drying of Probiotic Bacteria and Evaluation of the Product Quality
Published on: April 7, 2023
Effect of drying techniques on synbiotic encapsulation
Pothiyappan Karthik1,2, Ramasamy Rajam3, Ravi Sanjana1
1Department of Food Technology, Faculty of Engineering, Karpagam Academy of Higher Education, Coimbatore, 641 021 India.
None:
Synbiotic-based food formulations offer a promising approach to address nutritional deficiencies and enhance public health. This review highlights synbiotic encapsulation combining probiotics and prebiotics as a key innovation to improve the stability, viability, and bioavailability of beneficial microbes in functional foods. Various drying techniques such as freeze drying (FD), spray drying (SD), spray-freeze drying (SFD), refractance window drying (RW), and fluidized bed drying (FBD) are explored for their role in preserving microbial potency and prebiotic functionality. Each method presents unique advantages in extending shelf life, maintaining quality, and ensuring effective delivery. The review also examines prebiotic compounds that synergistically enhance probiotic activity, promoting digestive health and immunity. With rising consumer demand for functional and fortified foods, synbiotic encapsulation emerges as a transformative strategy for creating resilient, nutritious, and sustainable products. By addressing current challenges and highlighting technological advancements, this review offers comprehensive insights into the future potential of synbiotic encapsulation in food product development.
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Dehydration synthesis (also called a condensation reaction) is the chemical process in which two molecules covalently link together to form a new molecule, along with the release of a water molecule. Many physiologically important compounds form by dehydration synthesis reactions, such as complex carbohydrates, proteins, DNA, and RNA.
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