Related Experiment Video
Updated: May 19, 2026

10:44
Generating Whole Bacterial Genomes from Clinical Samples using a Target Enrichment Workflow
Published on: August 15, 2025
Draft genome sequencing of a Staphylococcus aureus clinical isolate from an inflamed wound
Ibrahim A Ahmed1, Zaid A Thabit2, Arif A Ghayyib3
1Applied Biology Department, College of Biotechnology, Al-Nahrain University, Baghdad, Iraq.
Microbiology Resource Announcements
|May 18, 2026
Abstract:
In this study, we isolated Staphylococcus aureus (SA8-IRQ) from a patient suffering from an inflamed wound at Al-Kadhimiya Hospital in Baghdad. The whole genome of the bacteria was sequenced and analyzed. It is 2.8 Mb in size, has 32.7% GC content, and contains several virulence and antimicrobial genes.
Related Concept Videos
Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Modern Molecular Taxonomy
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

