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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

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Related Experiment Video

Updated: May 19, 2026

Preclinical Positron Emission Tomography with Body Conforming Animal Molds for Cloud-Based Automated Image Analysis in Mice
07:45

Preclinical Positron Emission Tomography with Body Conforming Animal Molds for Cloud-Based Automated Image Analysis in Mice

Published on: October 25, 2024

Preclinical PET, PET/CT, and PET/MRI.

Sonja Schelhaas1, Michael Schäfers2,3

  • 1European Institute for Molecular Imaging, Multiscale Imaging Centre (MIC), University of Münster, Münster, Germany. sonja.schelhaas@uni-muenster.de.

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
|May 18, 2026
PubMed
Summary
This summary is machine-generated.

Preclinical positron emission tomography (PET) advances cancer research by visualizing molecular mechanisms. This technology aids in developing new diagnostic and therapeutic strategies for tumors.

Keywords:
Oncology modelsPositron emission tomographyPreclinical imagingSmall animal imagingTumor characterization

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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
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High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

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Last Updated: May 19, 2026

Preclinical Positron Emission Tomography with Body Conforming Animal Molds for Cloud-Based Automated Image Analysis in Mice
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Published on: October 25, 2024

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

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High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
11:09

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals

Published on: December 16, 2022

Area of Science:

  • Oncology
  • Medical Imaging
  • Molecular Biology

Background:

  • Tumors are a leading cause of death, necessitating a deeper understanding of their molecular progression for improved diagnosis and therapy.
  • Radioactive molecules detected by sensitive cameras, particularly in 3D, offer insights into these mechanisms.
  • Positron Emission Tomography (PET) utilizes positron-emitting radioisotopes to visualize molecular processes via specific radiotracers.

Purpose of the Study:

  • To provide an overview of the diverse applications of preclinical PET in oncology.
  • To discuss the challenges associated with preclinical PET in cancer research.
  • To highlight the role of preclinical PET in validating novel and existing imaging and therapeutic approaches.

Main Methods:

  • Utilizing small animal cancer models for preclinical studies.
  • Employing dedicated preclinical PET cameras, often in conjunction with CT or MRI.
  • Conducting in vitro experiments to prove tracer specificity before clinical application.

Main Results:

  • Preclinical PET has been instrumental in establishing novel imaging, diagnostic, therapy, and theranostic approaches.
  • The technology allows for thorough validation of both novel and clinically used radiotracers.
  • Integration with CT/MRI enhances the diagnostic and research capabilities of preclinical PET.

Conclusions:

  • Preclinical PET is a crucial tool in oncology research for understanding tumor progression.
  • It plays a vital role in the development and validation pathway for new cancer diagnostics and therapies.
  • Continued advancements in preclinical PET promise further improvements in clinical cancer care.