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Solitary Rectal Ulcer Syndrome Revisited: A Comprehensive Narrative Review
Krishanni Prabagar1, Pramodh Chitral Chandrasinghe2, S Janaki De S Hewavisenthi3
1Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, GQ, 10110, Sri Lanka.
Current Gastroenterology Reports
|May 18, 2026
Summary
Solitary rectal ulcer syndrome (SRUS) is a gastrointestinal disorder often misdiagnosed. This review provides a practical approach to diagnosing and managing SRUS, emphasizing individualized, multidisciplinary care.
Area of Science:
- Gastroenterology
- Colorectal Surgery
Background:
- Solitary rectal ulcer syndrome (SRUS) presents with diverse clinical, endoscopic, and histological features.
- It is frequently misdiagnosed as inflammatory bowel disease or rectal malignancy.
Purpose of the Study:
- To outline a practical approach for diagnosing solitary rectal ulcer syndrome.
- To guide the management of SRUS.
Main Methods:
- Comprehensive diagnostic approach including clinical history, digital rectal examination, endoscopy, histopathology, and physiological studies.
- Review of current treatment modalities for SRUS.
Main Results:
- Etiology of SRUS is multifactorial, potentially involving mucosal prolapse, ischemia, puborectalis contraction, and digital trauma.
- Treatment options range from lifestyle changes and biofeedback to surgery for refractory cases.
- Individualized and multidisciplinary management is crucial, especially in specific patient groups.
Conclusions:
- Accurate diagnosis of SRUS requires a thorough, multi-faceted evaluation.
- Effective management of SRUS involves a spectrum of interventions tailored to the individual patient.
- Further research and standardized protocols are needed for optimal SRUS care.
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