Agreement of anterior segment measurements between Scheimpflug and swept-source OCT based instruments

To evaluate the differences and interchangeability of white-to-white (WTW) distance and anterior chamber depth (ACD) measurements among three devices: Anterion (Heidelberg Engineering, Heidelberg, Germany), IOL Master 700 (Carl Zeiss Meditec, Jena, Germany), and Pentacam (Oculus, Wetzlar, Germany).

A randomized sample of 275 healthy subjects was selected. Measurements were taken of the right eye of all participants. WTW and ACD were measured using Anterion, Pentacam, and IOL Master 700. Differences between instruments were analyzed using the Friedman test, and device interchangeability was assessed using the Bland-Altman plots.

A total of 275 eyes of 275 subjects were evaluated. With regard to WTW analysis, statistically significant differences were found when comparing the three instruments (P<0.001). The highest values were obtained with IOL Master 700, followed by Anterion and Pentacam. For ACD, significant differences were also found among the three devices (P<0.001). The highest ACD measurements were obtained with Anterion, followed by Pentacam and IOL Master 700.

Significant differences in WTW and ACD measurements were found when comparing the three devices. The clinical relevance of these differences and the interchangeability of the instruments should be individually considered.