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Longitudinal Research02:20

Longitudinal Research

Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
Ending Relationships01:28

Ending Relationships

The dissolution of intimate relationships presents complex emotional and psychological challenges, particularly when emotional bonds are strong, the relationship is long-standing, and perceived alternatives are limited. This distress often intensifies in romantic breakups, where the initiator may experience greater turmoil than the rejected partner. Contributing factors include residual attachment, guilt over causing pain, and uncertainty about how to manage the situation. The stress is further...
Life Histories01:29

Life Histories

Overview
Social Exchange Theory02:06

Social Exchange Theory

We have discussed why we form relationships, what attracts us to others, and different types of love. But what determines whether we are satisfied with and stay in a relationship? One theory that provides an explanation is social exchange theory. According to social exchange theory, we act as naïve economists in keeping a tally of the ratio of costs and benefits of forming and maintaining a relationship with others (Rusbult & Van Lange, 2003).
Social Exchange Theory01:26

Social Exchange Theory

As formulated by John Thibaut and Harold Kelley, Social Exchange Theory explains human relationships as economic-like exchanges that maximize rewards and minimize costs. This theory suggests that individuals engage in relationships to gain benefits and reduce burdens, similar to economic transactions. It has been widely applied to various types of relationships, including romantic, professional, and social interactions.Rewards and Costs in RelationshipsRelationship rewards include emotional...
Relationship Growth01:27

Relationship Growth

Interpersonal relationships progress through stages, beginning with awareness and moving toward mutuality, where emotional connections deepen. While many relationships remain at moderate levels of mutuality, deeper connections form through self-disclosure, trust, and interdependence.Self-DisclosureSelf-disclosure involves revealing personal information, starting with surface-level details and gradually progressing to more intimate content. As trust grows, individuals feel more comfortable...

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Related Experiment Video

Updated: May 20, 2026

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling
06:04

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

Published on: January 17, 2025

BBB dynamics: the lifespan perspective.

Xuefang Sophie Ren1,2

  • 1Department of Neurosurgery, McGovern School of Medicine, University of Texas Health Science Center at Houston, 6431 Fannin St., Houston, TX, 77030, USA. Xuefang.ren@uth.tmc.edu.

Scientific Reports
|May 18, 2026
PubMed
Summary

The blood-brain barrier (BBB) is a dynamic system that changes throughout life, from development to aging. Understanding its evolution is key for effective drug delivery and preventing neurological disorders.

Area of Science:

  • Neuroscience
  • Vascular Biology
  • Pharmacology

Background:

  • The blood-brain barrier (BBB) was traditionally viewed as a static protective barrier.

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  • Recent research reveals the BBB is a dynamic system with properties changing across the lifespan.
  • These dynamics impact central nervous system (CNS) drug exposure and neurological conditions.