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Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.

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Related Experiment Video

Updated: May 20, 2026

Using Brain Activation (nir-HEG/Q-EEG) and Execution Measures (CPTs) in a ADHD Assessment Protocol
13:09

Using Brain Activation (nir-HEG/Q-EEG) and Execution Measures (CPTs) in a ADHD Assessment Protocol

Published on: April 1, 2018

Cross-training digital therapeutics for pediatric ADHD: study protocol for a randomized controlled trial.

Xi Zhao1, Yuanhao Cai2, Xia Zhang1

  • 1Department of Pediatrics, Shanghai Jing'an District Zhabei Central Hospital, Zhonghua Xin Road No.619, Jing'an, Shanghai, 200070, China.

Trials
|May 19, 2026
PubMed
Summary

This study evaluates a novel digital therapeutic (DTx) combining neurofeedback and executive function training for children with Attention-Deficit/Hyperactivity Disorder (ADHD). Results may offer a new non-pharmacological treatment option for ADHD symptoms.

Keywords:
Attention-deficit/hyperactivity disorderDigital health interventionDigital therapeuticsExecutive functionMethylphenidateNeurofeedbackRandomized controlled trial

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Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)
10:02

Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)

Published on: March 12, 2020

Area of Science:

  • Pediatric neurology
  • Digital health interventions
  • Cognitive neuroscience

Background:

  • Attention-Deficit/Hyperactivity Disorder (ADHD) significantly impacts children's academic, social, and safety outcomes.
  • Current digital therapeutics (DTx) for ADHD often target single mechanisms, potentially missing synergistic benefits.
  • This research investigates a novel cross-training DTx integrating neurofeedback and executive function training for pediatric ADHD.

Purpose of the Study:

  • To evaluate the effectiveness and acceptability of a cross-training digital therapeutic (DTx) for children aged 6-12 with ADHD.
  • To compare the DTx intervention against standard medication and a combination approach.
  • To assess improvements in core ADHD symptoms as measured by the Swanson, Nolan, and Pelham Rating Scale (SNAP-IV).

Main Methods:

  • A multicenter, open-label, randomized controlled trial involving 210 children aged 6-12 with ADHD.
  • Participants were randomized into three groups: medication (MED), DTx (DTX), or combination (COM).
  • The primary outcome was the change in SNAP-IV total score from baseline to 8 weeks post-randomization, with non-inferiority and superiority analyses planned.

Main Results:

  • This section is not available in the provided abstract.

Conclusions:

  • The study protocol details a randomized controlled trial to assess a novel cross-training DTx for pediatric ADHD.
  • The findings aim to determine the efficacy and acceptability of this integrated approach.
  • Results may support the development of new non-pharmacological or supplementary treatment options for children with ADHD.