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Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
Pharmacological augmentation for people with treatment-resistant depression
Rebecca Strawbridge1, Viktoriya L Nikolova1, Michael Browning2
1Department of Psychological Medicine, https://ror.org/0220mzb33Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
None:
Long-term pharmacological augmentation is central to care for treatment-resistant depression, yet until recently no adequately powered trials have examined it. With three such studies now published, we highlight the hope they offer for improving outcomes in this underserved population while highlighting caution in interpreting their collective findings without careful consideration of methodology and clinical context. We consider these issues and their implications for guiding more personalised treatment decisions aimed at sustained benefit in routine practice.
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