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Related Concept Videos

Aggression01:47

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Humans engage in aggression when they seek to cause harm or pain to another person. Aggression takes two forms depending on one’s motives: hostile or instrumental. Hostile aggression is motivated by feelings of anger with intent to cause pain; a fight in a bar with a stranger is an example of hostile aggression. In contrast, instrumental aggression is motivated by achieving a goal and does not necessarily involve intent to cause pain (Berkowitz, 1993); a contract killer who murders for hire...
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People can go to great lengths to protect their self-image and present themselves in ways that they want others to see them. Sociologist Erving Goffman presented the idea that a person is like an actor on a stage. Calling his theory dramaturgy, Goffman believed that we use “impression management” to present ourselves to others as we hope to be perceived. Each situation is a new scene, and individuals perform different roles depending on who is present (Goffman, 1959). Think about the way you...
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Affiliation motivation is the intrinsic desire to connect with others and belong to a social group, which plays a crucial role in forming and maintaining personal relationships. This type of motivation is essential for psychological well-being, as it provides individuals with a sense of community and support. An example of this is a student who joins a study group in order to feel a sense of connection. People with high affiliation motivation actively seek social approval, take satisfaction in...
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Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
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A Conflict Model of Reward-seeking Behavior in Male Rats
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Exploring the Psychological Mechanisms of Self-Aggression in Male Individuals with Substance Use Disorders: A Study

Youping Chen1, Yong Xin1, Wei Xin2

  • 1Department of Applied Psychology, School of Medicine, Southwest University of Science and Technology, Mianyang, China.

Substance Use & Misuse
|May 19, 2026
PubMed
Summary

Childhood trauma influences self-aggression in males with substance use disorders. Meaning in life acts as a barrier, while sensation seeking acts as a facilitator, mediating this relationship.

Keywords:
Childhood traumaautomated machine learninginterpretabilityparallel mediation modelself-aggressionsubstance use disorders

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Area of Science:

  • Psychology
  • Neuroscience
  • Machine Learning

Background:

  • Substance use disorders are frequently associated with self-aggressive behaviors.
  • The psychological underpinnings of self-aggression in substance use disorders, particularly in males, require further elucidation.
  • Childhood trauma is a significant risk factor linked to self-aggression in this population.

Purpose of the Study:

  • To explore the psychological mechanisms linking childhood trauma to self-aggression in males with substance use disorders.
  • To identify key psychological factors mediating this relationship using explainable machine learning.
  • To develop a conditional process model for understanding self-aggression in this demographic.

Main Methods:

  • Utilized data from 479 males in a compulsory detoxification facility.
  • Employed Auto machine learning (AutoML) for initial variable analysis and feature importance.
  • Applied explainable machine learning (SHAP) to identify significant psychological mediators.
  • Constructed a parallel mediation model to examine the roles of identified factors.

Main Results:

  • AutoML model achieved a Mean Absolute Error (MAE) of 2.338.
  • Key psychological features identified: Meaning in Life, Childhood Trauma, and Sensation Seeking.
  • Meaning in Life mediated the relationship between childhood trauma and self-aggression as a barrier.
  • Sensation Seeking mediated the relationship between childhood trauma and self-aggression as a beneficial factor.

Conclusions:

  • Meaning in Life and Sensation Seeking play significant mediating roles in the pathway from childhood trauma to self-aggression in males with substance use disorders.
  • Findings provide a foundation for developing targeted therapeutic interventions.
  • Understanding these mediators can inform strategies to reduce self-aggression in individuals with substance use disorders.