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Updated: May 20, 2026

Generation and Genetic Manipulation of Human Cervical Organoids
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Generation and Genetic Manipulation of Human Cervical Organoids

Published on: March 10, 2026

Plant-Derived Pathway Modulators: A Natural Strategy to Combat Cervical Cancer.

Md Zamshed Alam Begh1, Mehrukh Zehravi2, Sherouk Hussein Sweilam3,4

  • 1Department of Pharmacy, Faculty of Health and Life Sciences, Daffodil International University, Dhaka 1207, Bangladesh.

Current Topics in Medicinal Chemistry
|May 19, 2026
PubMed
Summary
This summary is machine-generated.

Phytocompounds from plants show promise in preventing and treating cervical cancer (CC) by targeting molecular mechanisms. Further research into these plant-based therapies could improve patient outcomes.

Keywords:
ApoptosisCervical cancerClinical studiesOxidative stress.PhytocompoundsSignaling pathways

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Published on: January 19, 2022

Area of Science:

  • Oncology
  • Pharmacology
  • Molecular Biology

Background:

  • Cervical cancer (CC) presents a significant global health challenge with high mortality rates.
  • Current treatments for advanced metastatic CC include surgery, radiotherapy, and chemotherapy.
  • Plant-derived compounds (phytocompounds) are emerging as potential therapeutic and preventative agents for CC.

Purpose of the Study:

  • To provide a comprehensive review of the molecular mechanisms underlying the anticancer properties of various phytocompounds.
  • To explore the impact of phytocompounds on key signaling pathways, molecular interactions, metastasis inhibition, cell cycle control, and apoptosis in CC.
  • To highlight preclinical and clinical findings on phytochemicals as adjuvant therapy for CC.

Main Methods:

  • Literature review of studies on phytocompounds and their effects on cervical cancer.
  • Analysis of molecular mechanisms, including signaling pathways and cellular processes.
  • Evaluation of preclinical and clinical evidence for phytochemical efficacy.

Main Results:

  • Phytocompounds demonstrate anticancer properties through various molecular mechanisms.
  • These compounds influence metastasis inhibition, cell cycle regulation, and apoptosis.
  • Promising preclinical and clinical data suggest potential for phytochemicals as adjuvant CC therapy.

Conclusions:

  • Plant-based interventions and phytocompounds are effective and well-tolerated in CC therapy.
  • Phytochemicals show significant therapeutic potential in CC, integrating molecular and clinical evidence.
  • Further research into plant-based treatments is crucial for advancing CC prophylaxis and therapy to improve patient outcomes.