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Related Experiment Video

Updated: May 20, 2026

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model
13:04

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model

Published on: March 18, 2015

PCI after SVG failure-native vessel or graft?

Pradeep Narayan1

  • 1Department of Cardiac Surgery, Rabindranath Tagore International Institute of Cardiac Sciences, Narayana Health, 124, EM Bypass, Mukundapur, Kolkata, 700099 India.

Indian Journal of Thoracic and Cardiovascular Surgery
|May 19, 2026
PubMed
Summary

Percutaneous coronary intervention (PCI) of saphenous vein grafts (SVG) showed better outcomes than native vessel PCI in a recent trial. This challenges current guidelines recommending native vessel intervention for SVG failure after bypass surgery.

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Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Clinical Trials

Background:

  • Saphenous vein graft (SVG) failure is a common complication after coronary artery bypass grafting (CABG).
  • Re-intervention is often necessary, but treatment strategies remain debated.
  • Current guidelines suggest prioritizing percutaneous coronary intervention (PCI) of the native coronary artery over SVG-PCI.

Purpose of the Study:

  • To compare the efficacy and safety of SVG-PCI versus native coronary artery PCI in patients with prior CABG and SVG failure.
  • To provide evidence to inform treatment guidelines for SVG failure.

Main Methods:

  • The PROCTOR trial was a randomized controlled trial.
  • It compared SVG-PCI directly with native coronary artery PCI.
Keywords:
Coronary artery stenosisPercutaneous coronary interventionSaphenous vein grafts

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Related Experiment Videos

Last Updated: May 20, 2026

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model
13:04

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model

Published on: March 18, 2015

Implantation of Inferior Vena Cava Interposition Graft in Mouse Model
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Implantation of Inferior Vena Cava Interposition Graft in Mouse Model

Published on: June 4, 2014

Implantation of Tissue-Engineered Vascular Graft in Mouse Carotid Artery via Cuff Technique
07:13

Implantation of Tissue-Engineered Vascular Graft in Mouse Carotid Artery via Cuff Technique

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  • Outcomes were assessed at 1-year follow-up.

    • Main Results:

    • SVG-PCI demonstrated significantly lower rates of major adverse cardiac events (MACE) at 1 year compared to native vessel PCI.
    • This suggests SVG-PCI may be a superior re-intervention strategy in select patients.

    Conclusions:

    • The PROCTOR trial findings challenge existing guideline recommendations.
    • SVG-PCI may be a favorable option for re-intervention in SVG failure.
    • Longer-term follow-up data are needed to confirm these results.