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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
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Flow Cytometry for Diagnosing Sézary Syndrome When Skin Biopsies Are Inconclusive: A Case Report

Abdelhafid El Mrahi1, Souha Denna1, Mohammed Bensalah2

  • 1Dermatology, Mohammed VI University Hospital, Medical School of Oujda, Mohammed First University, Oujda, MAR.

Cureus
|May 19, 2026
PubMed
Summary

Flow cytometry (FC) is crucial for diagnosing Sézary syndrome (SS) when skin biopsies are inconclusive. This method detects aberrant T-cells, confirms clonality, and aids in staging and treatment monitoring for improved patient outcomes.

Keywords:
cutaneous t-cell lymphomadiagnosticflow cytometrysézary syndrometnmbtrbc1

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