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Updated: May 20, 2026

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics
Published on: May 11, 2016
[Clear cell carcinoma of the cervix in Mauritania: a case report]
Ahmed El Heiba Mamina1, Khadijetou Vilaly2, Ekht Elbenina Zein3
1Faculté de Médecine, de Pharmacie et d'Odonto-Stomatologie, Service d'Anatomie et de Cytologie Pathologique, Centre National d'Oncologie, Nouakchott, Mauritanie.
Abstract:
Clear cell carcinoma (CCC) of the cervix is a rare cancer, particularly in the absence of exposure to diethylstilbestrol (DES). This case is unique because it involves a 40-year-old patient with no history of DES exposure, illustrating the diagnostic and therapeutic challenges in a resource-limited setting such as Mauritania. The patient presented with persistent vaginal bleeding, and a mass was detected during a gynaecological examination. The final diagnosis of CCC was confirmed by histopathological and immunohistochemical examination. Treatment consisted of external radiotherapy and chemotherapy, followed by an extended colpohysterectomy, without the use of brachytherapy because of technical constraints. The patient responded well to treatment, with no clinical or radiological evidence of recurrence. This case underscores the feasibility of effective multidisciplinary management of rare cervical tumors in resource-limited settings.