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Updated: May 20, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 17, 2014
Recurrent/Refractory Multidrug- and Pre-Multidrug-Resistant Pseudomonas aeruginosa Infection Cases Maintained by
1Division of Infectious Diseases and Infection Control, Saitama Medical University International Medical Center, Hidaka City, Saitama, Japan.
Multidrug-resistant Pseudomonas aeruginosa (MDRP) infections in an adult and a child were successfully managed with long-term, low-dose macrolide therapy after initial antibiotic treatments failed. This approach may influence pathogen colonization and host immunity.
Area of Science:
- Infectious Diseases
- Clinical Microbiology
- Pharmacology
Background:
- Multidrug-resistant Pseudomonas aeruginosa (MDRP) poses a significant treatment challenge, often developing after inadequate broad-spectrum antibiotic use.
- Pre-multidrug-resistant Pseudomonas aeruginosa (pre-MDRP) is defined by resistance to key antibiotic classes, including carbapenems, fluoroquinolones, and aminoglycosides.
- Pseudomonas aeruginosa infections require careful management, especially in vulnerable patient populations.
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